Job Description
About Athebio
Athebio AG is a biotechnology company pioneering drug discovery and protein engineering through its proprietary Athebody platform. We develop next-generation biotherapeutics, including targeted delivery systems (e.g., LNP, AAV) and radiotherapeutics, in collaboration with leading biotech and pharmaceutical partners.
Role Summary
As a Principal Research Associate in the Protein Science team, you will play a key hands-on laboratory role to support therapeutic candidate profiling and the development of innovative protein-based biotherapeutics. You will contribute scientific expertise across protein characterization, assay development, and protein production while working in a dynamic and collaborative biotech environment.
Key Responsibilities
* Perform hands-on laboratory work in protein characterization, assay development, and protein production.
* Conduct therapeutic candidate profiling using biochemical and biophysical techniques.
* Develop, execute, and optimize ELISA and BLI assays for protein characterization and functional analysis as well as additional analytical methods including SEC, IEX, HIC, and CD.
* Analyze, interpret, and document experimental data; prepare reports and present results to internal teams and external partners.
* Perform small-scale protein expression in E. coli and purification to support analytical and discovery workflows.
* Collaborate effectively across teams, maintain high scientific standards, and adapt efficiently to changing priorities.
Qualifications
* Degree in life sciences (e.g., biochemistry, protein science, biotechnology) or equivalent technician training, with ≥8 years of relevant professional experience; industry experience is an advantage.
* Strong hands-on experience in microbial protein production (especially E. coli at MTP scale), protein purification, and characterization using the methods listed above.
* Strong background in biotherapeutic discovery and candidate profiling.
* Ability to work independently and proactively in a fast-paced biotech environment.
* Excellent communication and collaboration skills.
* Proficiency in English, both written and spoken.
What We Offer
* An exciting opportunity to take responsibility and grow professionally and personally within an early-stage biotech company.
* The ability to actively contribute to and shape the development of the organization.
* Exposure to and collaboration with world-leading experts in DARPin technology.
* A diverse and multifaceted role within a highly collaborative and innovative environment.
Our Location
* Join us at our state-of-the-art facility in the Bio-Technopark Schlieren, Zurich.
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