Branche:
Ingenieurwesen
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We are looking for Associate Oligonucleotides Analytics (m/w/d) (LSB) - BS
Location: Basel | Workload: 100% | Start: 01 May 2026 | Duration: 12 months | Extension: possible | Home Office: max. 10% | Criminal record extract: not required | Travel: no | Barrier‑free workplace: no
Background
Behind every clinical trial product and commercialized medicine at Roche stands Pharma Global Technical Operations – an organization of over 10,000 employees worldwide. Within it, Pharma Technical Development plays a crucial role in advancing new medicines through innovation, collaboration, and scientific excellence.
The Synthetic Molecules Technical Development (PTDC) unit drives the technical development of Roche's synthetic molecules pipeline, covering drug substance, drug product, and analytical sciences. PTDC also manufactures clinical supplies for global clinical studies.
The position sits within Analytical Research and Development for Synthetic Molecules, responsible for designing and optimizing efficient analytical methods using state‑of‑the‑art technologies such as HPLC, GC, IC, and MS. The ultimate goal is to build robust control strategies for clinical trial material and eventually commercial supply.
The Ideal Candidate
The ideal candidate has completed a vocational scientific qualification (e.g. apprenticeship, laboratory technician, Chemielaborant) and brings 2?3 years of pharmaceutical industry experience, with a clear focus on analytical development for oligonucleotides. They offer strong hands‑on skills in HPLC, MS, and ideally LC‑MS, combined with an excellent quality mindset, attention to detail, and the ability to work effectively in a dynamic, innovative environment. This person is motivated to focus primarily on laboratory work and communicates confidently in English.
Tasks & Responsibilities
* Perform routine analytical measurements for Oligonucleotides (primarily HPLC with UV and/or Single Quadrupole MS detection)
* Plan, execute, and document experiments in close collaboration with a team of five associates
* Operate analytical instruments using chromatographic data systems such as Empower or OpenLab
* Evaluate data using Genedata or Oligo Analysis Accelerator
* Develop, optimize, and validate analytical methods for quality assessment of Oligonucleotides
* Ensure compliance with GxP guidelines and relevant SOPs
Must Haves
* Completed vocational scientific qualification (e.g. apprenticeship as chemical laboratory technician); no university degree (no Bachelor/Master/PhD)
* 2?3 years of experience in the pharmaceutical industry
* Hands‑on experience with analytical instrumentation/techniques (HPLC, MS)
* Strong interest or background in analytical development for oligonucleotides
* Knowledge of LC‑MS is a plus
* Experience with large molecule/biologics analytics is an advantage
* Self‑motivated, proactive, open‑minded, goal‑oriented, and a strong team player
* Strong quality mindset, attention to detail, and good knowledge of GxP requirements
* Good command of English; German is beneficial
Next Steps
Interview process:
* 1 interview round online
* 2 onsite interviews
Important: The job posting will be halted on 05 March 2026 at 15:10.
Additional Information
* Please upload the degree/apprenticeship certificate and your latest reference letter.
* Only contractors with completed vocational education can be considered.
* CVs must be submitted in English.
* This job advertisement may be subject to Swiss job registration requirements. If applicable, the posting period will be extended by 2 working days.
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