Overview
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We are looking for a Senior Research Associate In vivo Nicht-maligne Hämatologie m/w/d Metropolregion Basel
Background
Our research group focuses on the development and evaluation of innovative gene therapy approaches targeting non-malignant hematological disorders such as bleeding diseases, thrombotic conditions, and different forms of anemia. The team investigates the efficacy, safety, and translational potential of novel therapeutic strategies using both animal models and human biological samples.
In this role, you will contribute to preclinical research programs by supporting experimental studies involving in vivo disease models as well as ex vivo and in vitro assays. Working within a collaborative research team, you will generate and analyze data to characterize emerging gene therapy candidates and their impact on hemostasis and thrombosis.
The position combines hands-on animal experimentation with laboratory-based analytical work, covering the entire workflow from study preparation and execution to sample analysis and documentation.
Responsibilities
* Plan, perform, and evaluate in vivo experiments in rodent models, including procedures such as intravenous injections, blood sampling, plasma collection, and thrombosis or bleeding model studies
* Assess the efficacy and safety of novel gene therapy candidates using molecular and biochemical assays
* Conduct laboratory assays such as ELISA, thrombin generation assays, and chromogenic assays using murine and human samples
* Process and analyze patient-derived biological material, including blood and plasma, in ex vivo and in vitro experimental settings
* Perform data analysis and communicate findings within the project team
* Maintain accurate experimental documentation and support general laboratory organization, safety standards, and inventory management
Candidate Profile
We are looking for a motivated research associate with practical experience in in vivo experimentation and laboratory research within a collaborative scientific environment.
The ideal candidate has a background in life sciences and demonstrates strong technical expertise in animal handling and experimental study execution.
Required Qualifications
* MSc or BSc degree in Life Sciences for example molecular biology, immunology, pharmacology, or coagulation biology with 23 years of hands-on animal study experience
or
* Completed apprenticeship as a Research Associate / Laboratory Technician with 45 years of academic or industry experience
* Active LTK1 certification or FELASA equivalent for animal experimentation
* Proven experience working with rodents, including intravenous injections and blood collection
* Solid experience in experimental design, data interpretation, and scientific documentation
* Ability to independently plan and execute in vivo studies from preparation to completion
* Fluency in English
Note: Candidates with a PhD are not considered for this role.
Preferred Qualifications
* Experience with animal surgery procedures
* Knowledge of coagulation biology, hemostasis, or gene therapy approaches
* Practical experience with biochemical and molecular assays such as ELISA, thrombin generation assays, or chromogenic assays
* Previous experience working in an industrial research environment
Project & Role Information
Start Date: May 1st, 2026
Latest Possible Start Date: Candidates with up to 3 months notice period can be considered
Contract Duration: 12 months
Contract Extension: Unlikely depending on project development and available budget
Work Location: Basel fully on site
Workload: 100
Home Office: Not planned only in exceptional cases
Travel: None
Team Structure: Approx. 15 people in the group, 4 within the project team
Hiring Manager: David Tovo / Nina Frey
Department: Cardiovascular Metabolism Immunology PA
Working Hours: Standard working hours
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