Main Responsibilities:
1. Design, execute, and analyze diverse in vivo experiments, including intravenous injections, blood and plasma collection, bleeding and thrombosis models, and related procedures
2. Characterize efficacy and safety of novel gene therapy assets using molecular and biochemical assays (e.g. ELISA, thrombin generation assay, chromogenic assays) in murine and human samples
3. Prepare, handle, and test patient-derived material (blood and plasma) in in vitro and ex vivo settings
4. Perform data analysis and present results within the team
5. Maintain thorough documentation and contribute to general lab organization, safety, and inventory management
Qualifications and Experience:
6. Relevant working/residency permit or Swiss/EU-Citizenship required
7. MSc or BSc in Life Sciences (e.g., molecular biology, pharmacology, immunology, coagulation) with at least 2-3 years' hands-on animal study experience (No PhD accepted) OR completed an apprenticeship as Research Associate (“Lehrabschluss”) with at least 4-5 years of academic or industry experience
8. Active LTK1 (FELASA or equivalent) certification
9. Demonstrated hands-on experience with rodent work, including intravenous injections and blood collection
10. Strong experience in experimental design and data analysis
11. Ability to independently execute and manage in vivo studies from start to finish
12. Fluency in English
Nice to Have:
13. Experience with animal surgery
14. Knowledge or experience in coagulation and/or gene therapy
15. Hands-on experience with molecular and biochemical assays (e.g. ELISA, thrombin generation, chromogenic assays)
16. Prior industry experience