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Senior ngs bioinformatician

Rolle
SOPHiA GENETICS
EUR 115’000 pro Jahr
Inserat online seit: 12 September
Beschreibung

Job Opportunity: Senior NGS Bioinformatician at SOPHiA GENETICS

Are you an experienced Bioinformatician specializing in NGS data analysis? Ready to take on impactful new projects at the forefront of precision medicine?

If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Bioinformatic Product Development team as our Senior NGS Bioinformatician, and help us make a positive impact on cancer and rare disease patients worldwide.

This role is a hybrid opportunity, requiring 3 days onsite at our corporate office in Rolle, CH.


Our Mission

We believe in a smarter, more data-driven approach to healthcare decisions. Our cloud-native AI-powered SOPHiA DDM Platform makes that vision a reality daily. You will contribute directly to our mission to democratize data-driven medicine for the benefit of cancer and rare disease patients globally.


Your Mission

As our Senior NGS Bioinformatician, you will lead data exploration efforts to address practical questions during product development. You will work with diverse datasets varying by gene panel, sample type, enrichment technology, sequencing platform, and more. Your work involves assessing NGS kit and chemistry performance, evaluating analytical accuracy, and conducting in-depth analyses that will influence product evolution, including proposing improvements to probe design, analytical tools, and pipeline architecture.


The Value You Bring

* Run SOPHiA GENETICS NGS pipelines in default mode
* Modify scripts/modules manually for research purposes
* Understand functions of each script/module in the pipeline
* Perform quality assessments and analytical performance evaluations on different chemicals or platforms
* Conduct data exploration to answer practical questions related to product feasibility
* Explore new technical/biological features (e.g., UMI diversity) and present insights
* Analyze datasets from collaborators and deliver timely exploration results
* Participate in discussions and present results to collaborators and at conferences
* Prepare and present NGS analysis results to clients and at workshops


Minimum Requirements

* At least 4 years post-Doctoral experience in Bioinformatics, Computational Biology, or related field; or PhD with relevant experience
* Extensive experience with targeted sequencing data analysis
* Hands-on NGS data analysis experience
* Experience with regulated medical device development is a plus
* Strong background in cancer cell biology is a plus
* Excellent communication and presentation skills in English; additional languages are an asset

You will join an organization with a patient-centered approach, driven by purpose and growth.


Our Recognitions & Benefits

* Top 10 most innovative companies worldwide
* Top 50 smartest companies globally
* 100 Best Places to Work in Boston (2022-2025)
* Top 10 European Tech Startup
* Top 10 European biotech startups to watch
* Top 25 East-Coast Biotech to watch

Our benefits include health coverage, meal vouchers, a vibrant work environment with amenities, free parking, a social committee, and direct interaction with leadership.


Our DNA & Virtues

We are interconnected, curious, resilient, nimble, and adventurous. Our Virtues—Decide, Do, Collaborate, Innovate, Empower, Adapt, Learn—guide our actions. Our mantra, We Care, underscores our compassionate mission.

Start date: ASAP

Location: Rolle, Switzerland (Hybrid: 3 days/week)

Contract: Permanent

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