PpAt Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. /p h3The Position /h3 h3Who We Are /h3 pPharma Global Technical Operations (PT) is the organization that manufactures and delivers Roche’s groundbreaking therapies to millions of patients worldwide. PT is involved in producing every Roche medicine from the development process through clinical trials and continuing to product maturity. Our organization coordinates all aspects of the production of Roche medicines in all disease areas and dosage forms. /p pPharma Technical Development (PTD) is an integral part of this mission. As an organization of over 2,500 people globally, PTD is responsible for developing the manufacturing processes, products, analytical methods, and Chemistry, Manufacturing Controls (CMC) strategies to deliver all new products in Roche’s pipeline. This work encompasses the full range of development functions, including biologics, synthetic molecules, devices, clinical supply chain management, and project and portfolio management. PTD applies leading technical expertise to design, develop, supply, and register clinical-stage products globally, reliably delivering the pipeline and supporting commercial manufacturing operations. We excel through innovation, collaboration, dedication, and mutual respect, continuously improving what we do to ensure Roche’s supply of quality products to patients. We commit ourselves to scientific rigor, technical excellence, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. /p h3Position Purpose /h3 pAs the Global Head of Pharma Technical Development Synthetic Molecules (PTDC), you are an enterprise leader responsible for the strategic direction, development, clinical manufacturing of Roche’s Synthetic Molecule portfolio. This is a triple-impact role: you lead the end-to-end technical development (CMC) for small molecules, oligonucleotides and peptides, while simultaneously serving as the PTD Basel Site Head. /p pYou are also responsible for internal manufacturing of launch and commercial supply of drug substance for the synthetic molecules. /p pYou are the primary accountable leader of the new Synthetic Molecule Facility (SMF), ensuring it is delivered on time and on budget to deliver Pharma Ambition. You act as a catalyst for “Collective Leadership” within PTD, bridging the gap between early-stage innovation and commercial launch excellence. /p h3Key Responsibilities /h3 ul liSynthetic Molecule Portfolio End-to-End Development /li liE2E Accountability: Lead the vision and execution for synthetic molecule drug substance, from discovery support and clinical manufacturing to commercial launch and lifecycle management /li liLaunch Excellence: Ensure "Right First Time" (RFT) delivery of CMC packages for NMEs (New Molecular Entity) and Line Extensions, directly contributing to Roche's overall goals and RD Excellence goals /li liTechnical Innovation: Drive next-generation synthetic capabilities, including digital automation, "Lab to Plant" models, and sustainable "Green Chemistry" processes /li liBasel Site Leadership (PTD Site Head) /li liSite Governance: Serve as the single point of accountability for all PTD site-related matters in Basel. This includes oversight of Quality, Safety, Sustainability, and Infrastructure. /li liActive Basel/Kaiseraugst Management Team member: Effectively representing and advancing PTD and Site interests at the Basel Kaiseraugst Management Meeting. /li liPeople Culture: Foster a High Performing Organization (HPO). Lead employee training, engagement initiatives, and cultural transformation to make Basel a talent magnet for the global PT network. /li liInfrastructure Management: Oversee the operational health of all PTD Basel labs and pilot plants, ensuring they meet evolving portfolio needs /li liOwns Basel site IT/OT investments related to ASPIRE, Cybersecurity and Business Continuity, and is accountable for associated delivery /li liSynthetic Molecule Facility (SMF) Project Owner /li liFull Delivery Responsibility: You are responsible in full for the new Synthetic Molecule Facility. This includes meeting all milestones: on time, on budget, and fully compliant. This facility is the flagship facility that will accelerate technical development with modern digital capabilities /li liOperational Readiness: Ensure a seamless transition from construction to clinical/commercial production, ensuring the facility is integrated into the global Clinical Supply Center (CSC) and commercial Drug Substance network /li liPT SHE Governance SPOC /li liPT SHE Council: Serve as the Senior Point of Contact (SPOC) for the PT Safety, Health, and Environment (SHE) Council /li liPTD SHE Chair: Chair the PTD SHE Governance body. Drive the "Roche Strategy for SHE" across the four geographies (Penzberg, Kaiseraugst, Basel, South San Francisco (SSF)), prioritizing carbon footprint reduction and zero-accident culture through safety behaviors /li liCommunity Leadership Collective Leadership /li liPT/D Community Influence: Partner across the PT and PTD network to simplify the landscape and remove silos /li liHigh Performing Organization: Being a role model in talent and leadership development across PT/D /li liStrategic SPOC: Act as the primary partner for RD units and Late Stage Portfolio Committee (LSPC) members regarding synthetic molecule viability and technical risks /li li100PY Productivity: Embed Lean/OE principles to achieve 100PY targets, ensuring the organization scales capacity without proportional cost increases /li /ul h3Who You Are /h3 ul liPh.D. in Chemistry, Chemical Engineering, or related Life Sciences field with equivalent relevant work experience in a global setting /li liExtensive years in the Pharmaceutical industry, with many years in senior executive leadership. Deep expertise in Synthetic Molecule CMC (Small Molecules/Oligos/peptides) and Parenteral operations are preferable /li liSeasoned leader, role modeling A "Visionary, Architect, Catalyst, Coach" (VACC) leadership. Proven ability to lead through others in a matrixed, global environment. Strong ability of motivating and inspiring others /li liDemonstrated track record of delivering large-scale capital projects (e.g., manufacturing facilities) on time and budget /li liStrong experience in managing complex sites, including SHE, Quality, and employee engagement responsibilities. Track record of excellent stakeholder management experience /li liExceptional ability to influence and foster constructive relationships with Head of RD units and Global Technical Operations leaders, outstanding communication skills across all levels /li /ul h3Success Metrics /h3 ul liCMC Delivery: Deliver our early and late stage Portfolio on time RFT. /li liRFT Launch: No first-cycle approval delays due to synthetic drug substance CMC issues /li liSynthetic Molecule Facility (SMF) Delivery: Facility completion and validation according to the master schedule /li liQuality Assurance (QA) SHE Performance: Meeting or exceeding PTD compliance, sustainability and safety targets /li liEmployee Engagement: Verifiable people development growth in Basel site and PTD engagement scores and retention. /li /ul h3Who we are /h3 pA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. /p pbRoche is an Equal Opportunity Employer. /b /p /p #J-18808-Ljbffr