PhD Position in Biocatalysis and Enzyme Engineering
The University of Bern invites applications for a full‑time (100%) PhD position lasting four years, funded by the Swiss National Science Foundation. The position is part of a research group led by Prof. Rebecca Buller in the Department of Chemistry, Biochemistry and Pharmaceutical Sciences.
Your role
We are seeking a highly motivated PhD student to join our team and contribute to cutting‑edge research in biocatalysis and enzyme engineering. Our group develops innovative biocatalysts to advance the sustainability and efficiency of chemical and pharmaceutical synthesis. We aim to design and evolve enzymes that catalyze new‑to‑nature reactions, broadening the scope of biocatalytic transformations beyond those found in nature. By combining rational design, computational tools, and directed evolution, we seek to understand and exploit enzyme catalytic promiscuity for practical synthetic applications.
Your profile
* Master’s degree in Chemistry, Biochemistry, Biotechnology, or a closely related field
* Strong foundation in organic chemistry and enthusiasm for enzyme catalysis
* Ability to work in a team
Desirable experience:
* Synthetic chemistry and reaction optimization
* Site‑directed mutagenesis, molecular cloning, and protein expression/purification
* Enzyme engineering
* Analytical method development (e.g., HPLC, GC, MS)
* Protein bioinformatics and computational (bio)chemistry
We recognize that no single candidate will possess all these skills. The ideal candidate will be curious, proactive, and eager to expand their expertise in both experimental and computational methods during their doctoral studies.
We offer
* State‑of‑the‑art laboratory and university infrastructure
* Working in an international, supportive and inspiring environment
* Opportunities to attend national and international conferences, teaching and coaching
Application
We look forward to receiving your application by email to rebecca.buller@unibe.ch by Nov 30th, 2025.
It must include a letter of motivation (max 2 pages), a Curriculum Vitae and contact details of two references. Only complete applications compiled in a single PDF file will be considered.
Apply now
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