H4About us /h4pGRANITE BIO is a private biotechnology company located in Basel (Switzerland).brGRANITE BIO is supported by top-tier investors with ~$100M raised to date. Based on fundamental research conducted over the last two decades, GRANITE BIO’s is pursuing a differentiated approach to transform inflammatory, autoimmune, and fibrotic conditions. Both our programs are first-in-class monoclonal antibodies for large market opportunities in Immunology and Inflammation. GRT-001, the lead asset, depletes inflammatory monocytes. It has just completed a Phase 1a trial in healthy volunteers and has shown favorable safety and pharmacodynamic effect. The Phase 1b trial in patients with Ulcerative Colitis has just started. GRT-002 is an IL-3 neutralizing antibody that is thought to play an important role in type II inflammation.brWe are seeking a Data Scientist with strong expertise in data transfers (DTS), statistical analysis, and translational data integration to join our Translational Science team. This role supports the progression of programs in the early clinical development stage (Phase I).brIn this position, you will focus on the end-to-end lifecycle of data, including ingestion, harmonization, transfer, analysis, and interpretation of clinical PD, biomarker, and clinical datasets. You will play a key role in building scalable data pipelines, ensuring high-quality data transfers, and applying advanced statistical methods to generate actionable insights for first-in-human studies. /pbrh4Responsibilities /h4pstrongData Science Statistical Analysis /strongbr• Apply advanced statistical methods to analyze integrated preclinical, biomarker, and clinical datasetsbr• Develop and implement statistical models supporting translational and exploratory analysesbr• Contribute to and review Statistical Analysis Plans (SAPs) with a focus on early-phase and biomarker-driven studiesbr• Support decision-making (e.g., dose escalation, cohort expansion) through data-driven insightsbr• Perform exploratory analyses linking PD, biomarkers, and clinical outcomesbrstrongData Transfers Integration (DTS) /strongbr• Design, implement, and oversee data transfer specifications (DTS) across internal systems and external partnersbr• Ensure seamless ingestion and harmonization of multi-source datasets (preclinical, clinical, omics, biomarker)br• Establish and maintain robust ETL pipelines and data workflowsbr• Ensure data consistency, traceability, and auditability across systems and studiesbr• Collaborate with CROs and vendors to ensure timely, high-quality data delivery and transfersbrstrongData Management Quality /strongbr• Oversee data management activities for Phase I trials with emphasis on complex and exploratory datasetsbr• Define and enforce data standards, structures, and validation rules (e.g., CDISC where applicable)br• Review key documents (DMPs, CRFs, data transfer agreements/specifications, validation plans)br• Ensure data readiness for analysis, database lock, and regulatory submissionsbrstrongProcess Compliance /strongbr• Ensure compliance with ICH-GCP and relevant data standardsbr• Support regulatory documentation and submissions involving biomarker and translational databr• Contribute to the development of scalable, fit-for-purpose data science and DTS processes /ph4Qualifications /h4pbr• MSc or PhD in Data Science, Statistics, Biostatistics, Bioinformatics, or a related fieldbr• 5+ years of experience in data science, statistical analysis, or clinical/translational data environmentsbr• Strong experience with data transfers (DTS), ETL processes, and data pipeline developmentbr• Proficiency in statistical programming (e.g., R, Python, SAS)br• Experience with early-phase clinical developmentbr• Solid understanding of biomarkers, PK/PD relationships, and data integration across domainsbr• Familiarity with CDISC standards (SDTM/ADaM) and/or exploratory/non-standard datasetsbr• Experience with ICH-GCP and relevant standardsbr• Experience with clinical early phase studiesbrbr/ph4What we currently offer /h4pstrongPrime Location /strongbrOur modern laboratories and offices are located in Tech Park Basel – a leading hub for early-stage start-ups.brstrongCommuter Benefits /strongbrWe support your individual commuting needs with parking options or a commuter allowance.brstrongFlexible Working /strongbrWe offer flexible working arrangements where possible.brstrongAdditional Time Off /strongbrIn addition to 24 days of annual leave, our offices and labs are closed between Christmas and New Year.brstrongYour Birthday Off /strongbrEnjoy an extra day off to celebrate your birthday.brstrongCoffee Connection /strongbrFree coffee and a great space to connect with colleagues.brstrongPersonal Development /strongbrWe support your professional and personal growth.brstrongCreative Environment /strongbrWork in an innovative, dynamic, and creative setting.brstrongDiverse Team /strongbrJoin an international team of passionate and talented people.brstrongTeam Events /strongbrRegular off-site summer and winter events to connect and have fun together.brPlease note that these benefits are subject to change at the company’s discretion and do not constitute a contractual entitlement. /p