Senior Computational Toxicologist - Research Role
This is a unique opportunity to work in a highly interdisciplinary team that bridges cheminformatics, data science, toxicology, and drug development. As a senior computational toxicologist, you will apply state-of-the-art machine learning to address critical safety questions and contribute to the integration of diverse data types.
Main Responsibilities:
* Design and develop machine learning models to predict safety-relevant endpoints using chemical structure and biological data.
* Integrate chemoinformatics and in vitro safety data with potential expansion toward transcriptomics or other omics technologies.
* Provide in silico support for discovery and early development programs, offering scientific insights into potential safety risks.
* Leverage internal data and external knowledge bases to enhance model performance and interpretability.
* Collaborate closely with toxicologists, pharmacologists, data scientists, and chemists to co-create solutions and ensure models are meaningful and relevant.
Qualifications and Experience:
* Relevant working/residency permit or Swiss/EU-Citizenship required.
* PhD or MSc (with relevant experience) in Computational Toxicology, Cheminformatics, Bioinformatics, Data Science, Pharmacology, or a related field.
* Solid experience in developing machine learning models applied to chemical and biological data.
* Strong foundation in cheminformatics/chemistry, including working with molecular descriptors, chemical similarity, and structure-based analyses.
* Experience with toxicological datasets and safety endpoints such as DILI or nephrotoxicity.
* Familiarity with in vitro safety data and an interest in integrating complex biological datasets.
* Proficient in programming (e.g., Python, R) and using scientific computing libraries.
* Fluency in English and excellent communication and collaboration skills.
You will have the opportunity to be part of a highly respected organization at the forefront of drug discovery and development. The role offers a challenging and dynamic environment where you can utilize your expertise to make a significant impact.