Ph3Summary /h3 pInternal job title: Executive Director /p pLocation: Basel, Switzerland /p pAs the Head of Neurodegeneration within Translational Medicine, you will serve as a senior scientific and strategic leader responsible for shaping and delivering the translational strategy for neurodegenerative therapeutic programs. You will provide expert guidance bridging research, early clinical development, and biomarker/experimental medicine innovation to advance assets from discovery through proof‑of‑concept and into full development. /p pIn addition, you will lead or integrate global, cross‑functional teams to design, implement, and execute cutting‑edge translational strategies, and act as an influential thought partner in neurodegenerative disease biology, clinical development, and emerging therapeutic modalities. /p h3About The Role /h3 h3Key Responsibilities /h3 h3Strategic Leadership Scientific Direction /h3 ul liDefine and oversee the long‑term translational strategy for the Neurodegeneration Pillar, ensuring scientific excellence and alignment with broader BR and TM organizational priorities. /li liServe as a senior advisor and thought leader within neurodegeneration disorders, leveraging deep specialty expertise to inform program design, biomarker strategy, and patient‑relevant endpoints. /li /ul h3Program Portfolio Leadership /h3 ul liLead global translational teams across Phase I–IIa (“Discovery” through TDP), driving implementation of high‑quality development strategies in single or multiple neurodegeneration indications. /li liRepresent TM on global program teams (GPT) and decision boards, ensuring that neurodegeneration programs meet quality, regulatory, and differentiation objectives. /li /ul h3Translational Clinical Development Excellence /h3 ul liLead the design and execution of First‑in‑Human (FIH) and Phase IIa studies, working collaboratively with clinical, regulatory, biomarker, and profiling partners. /li liLeads the creation of clinical components of key documents e.g., Clinical Trial Protocols (CTPs), Investigator’s Brochures, Clinical Study Reports (CSRs), regulatory documents etc. with high levels of quality and consistency. /li /ul h3Leadership of People, Culture, and Matrix Teams /h3 ul liServe as a culture champion, promoting empowerment, innovation, and collaboration across TM and broader BR organizations. /li liMentor and develop scientific talent across translational and clinical functions. /li /ul h3External Impact Partnerships /h3 ul liLead interactions with external stakeholders (e.g., regulatory authorities, key opinion leaders, data monitoring committees, advisory boards etc.) and internal NVS stakeholders. /li liContribute to opportunity assessments and due diligence for neurodegeneration and adjacent therapeutic areas. /li /ul h3Governance, Compliance Documentation /h3 h3Essential Requirements /h3 ul liMD and PhD required with clinical subspecialty training in neurological diseases with deep expertise in neurodegeneration disorders. /li liA minimum of 10+ years of extensive experience in translational medicine, early clinical development, or experimental therapeutics. /li liDemonstrated success leading complex global programs and cross‑functional scientific teams. /li liProven ability to shape development strategies, execute early clinical studies, and influence regulatory/packages supporting differentiation. /li liExperience working in pharmaceutical/biotech company strongly preferred. /li /ul h3Desirable Requirements /h3 ul liDirect people management experience. /li /ul h3Accessibility And Accommodation /h3 pNovartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e‑mail to and let us know the nature of your request and your contact information. Please include the job requisition number in your message. /p pWhy Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? /p h3Benefits and Rewards: /h3 pLearn about all the ways we’ll help you thrive personally and professionally. /p pRead our handbook (PDF 30 MB) /p /p #J-18808-Ljbffr