Location: Basel, Switzerland (3-4 days per week onsite)
Employment Type: Permanent, Full-Time
About the Role
We are seeking an experienced Senior Clinical Project Manager to lead the operational delivery of global oncology clinical trials, with a particular focus on studies conducted across Europe and the United States. This role will be responsible for driving cross‑functional execution of clinical programs from study start‑up through database lock and study close‑out, ensuring delivery against timelines, budgets, and quality objectives
Key Responsibilities
Lead the planning, execution, and oversight of Phase I–III oncology clinical trials across the EU and US
Develop and maintain integrated study timelines, budgets, resource plans, and operational risk mitigation strategies
Serve as the primary operational lead for assigned clinical programs, ensuring alignment across internal and external stakeholders
Manage CROs, central laboratories, imaging providers, and other clinical vendors to ensure high‑quality study delivery
Coordinate study start‑up activities, including country selection, feasibility assessments, site activation, and enrolment planning
Drive cross‑functional study team meetings and provide regular updates to senior management and governance committees
Ensure studies are conducted in accordance with ICH‑GCP, FDA, EMA, and applicable local regulatory requirement
Partner with Regulatory Affairs to support clinical trial applications, protocol amendments, and submission‑related activities
Monitor study progress, recruitment, data quality, and budget performance, implementing corrective actions where required
Support inspection readiness activities and contribute to successful regulatory authority inspections and audits
Experience
Bachelor's degree in Life Sciences or related scientific discipline; advanced degree preferred.
Minimum 8 years of clinical operations experience within biotech, pharmaceutical, or CRO environments
Demonstrated experience leading multinational oncology clinical trials across Europe and North America
Strong understanding of FDA and EMA clinical development requirements and regulatory expectation
Experience managing global CRO partnerships and external vendor relationships
Previous responsibility for study budgets, timelines, and operational governance
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