Overview
Cryo-EM Specialist – Structural Biology role at Novartis. Location: Basel, Switzerland. Employment type: Full-time onsite.
We are recruiting a Principal Scientist with a strong background in Cryo-Electron Microscopy (Cryo-EM) to join the Basel team. The successful candidate will contribute to a dynamic and collaborative research environment, bringing scientific curiosity, motivation, collaboration, and strong organizational and communication skills.
Job Purpose
Novartis Discovery Sciences aims to pioneer innovative approaches for transformative therapies. The Protein Sciences group supports target-based drug discovery using biophysics, NMR, X-ray crystallography, and Cryo-EM to enable development of novel therapeutics.
Your Responsibilities Will Include
* Perform day-to-day operations within the EM group, including maintaining and operating high-end electron microscopy, structure determination, modeling, and interpretation of biologically and therapeutically relevant targets.
* Collaborate closely within the Protein Sciences group and with cryo-EM colleagues at Novartis globally.
* Stay up to date with the latest developments in cryo-EM technologies.
* Mentor and train new users in EM techniques and best practices.
* Maintain detailed records of experiments, instrument logs, and maintenance activities.
Minimum Requirements
* Ph.D. in a relevant scientific discipline with 5 years of experience or equivalent relevant research experience in academia or the pharmaceutical/biotech sector.
* Strong background in cryo-EM techniques including sample preparation, single-particle analysis, and modeling.
* Excellent communication and presentation skills in oral and written English, and German and/or French.
Desirable Requirements
* Proficiency in scripting and automated processing workflows.
* Ability to troubleshoot and optimize cryo-EM data pipelines for single-particle analysis.
* Familiarity with AI-based tools for construct design.
* Experience with expression, purification and modification of a range of protein targets.
* Experience in cryo-electron tomography and dual-beam scanning electron microscopy.
Why Novartis
Our purpose is to reimagine medicine to improve and extend people’s lives. We strive to be the most valued and trusted medicines company, driven by our people. Learn more at Novartis websites linked in the original posting.
You’ll Receive
Details on benefits and rewards are available in the Novartis Life Handbook and Benefits & Rewards resources linked in the original posting.
Commitment To Diversity And Inclusion
Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of patients and communities we serve.
Additional Contacts
Join the Novartis Network to stay connected with career opportunities: https://talentnetwork.novartis.com/network
Job Details
* Seniority level: Mid-Senior level
* Employment type: Full-time
* Job function: Research, Analyst, and Information Technology
* Industries: Pharmaceutical Manufacturing
#J-18808-Ljbffr