Company Description
This leading biopharmaceutical company, based in Vevey, Switzerland, is at the forefront of innovation in large-scale biologics manufacturing. Focused on supporting early-phase clinical programs, the site specializes in producing materials for Phase I and II clinical trials using cutting-edge technologies and scalable bioprocessing systems.
Job Description
As an Upstream Process (USP) Scientist, you will play a key role in supporting clinical manufacturing operations for biologics at scales ranging from 200L to 2000L. You will be responsible for executing pre-clinical and clinical campaigns, ensuring GMP and safety compliance, and contributing to the integration of new technologies and continuous improvement initiatives in cell culture processes.
Working closely with cross-functional teams, including Production, QA, QC, and Engineering, you will manage technical execution, batch documentation, deviation investigations, and support the implementation of optimized upstream processes.
Key Responsibilities
* Oversee and support cell culture operations (fed-batch and/or perfusion) in large-scale bioreactors.
* Perform Electronic Batch Record (EBR) reviews using the Manufacturing Execution System (MES).
* Lead and close deviations, investigations, CAPAs, and critical control point (CCP) actions in line with the site’s quality plan.
* Ensure adherence to GMP, safety protocols, and internal quality standards.
* Maintain up-to-date training records and comply with individual training requirements.
* Proactively report unexpected events and maintain full traceability of assigned tasks.
* Follow site EHS procedures and immediately report hazardous conditions or behaviors.
* Suggest process improvements and contribute to a culture of safety and quality.
Essential Requirements
* PhD in Biology, Biotechnology, or a related field with 1–2 years of industry experience OR MSc/Engineering degree with 4–5 years of relevant experience OR Technical degree with 10+ years of experience in GMP manufacturing.
* Strong expertise in fed-batch and/or perfusion cell culture processes.
* Working knowledge of GMP and BPF regulations.
* Proficiency in MES for electronic batch record reviews.
* Excellent communication and teamwork skills with the ability to collaborate across departments.
* English fluency required; French is a strong plus.
Desirable Experience
* Familiarity with TrackWise, SAP, LIMS, and standard office IT tools.
* Prior experience in clinical or commercial upstream bioprocessing.
* Demonstrated experience in deviation and CAPA management.
Additional Insights
* Location: Vevey, Switzerland (on-site role)
* Contract Type: Until End of the Year (with strong potential for extension)
* Start Date: ASAP
* Language Requirements: English required; French preferred
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