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von: F. Hoffmann-La Roche AG
At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
The Position
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche .
In Roche ́s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicine. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
The Therapeutic Modalities (TMo) function is part of the Roche Pharma Research and Early Development (pRED) organization. TMo discovers and optimizes innovative drug candidates including small molecules, biologics and nucleic acid-based therapeutics in order to deliver novel therapeutic approaches across all pRED Discovery and Translational areas (DTAs).
This position is located in Computer-Aided Drug Design (CADD), a group within Medicinal Chemistry research, where the computer-aided discovery of chemical starting points and further optimization towards clinical candidates is the primary focus. To ensure excellence in drug design, we push the scientific boundaries in key areas of CADD, implement new computational tools, distribute and train and advocate a digital mindset across the organization.
The Opportunity
We are offering a unique opportunity for a computational scientist to work with multidisciplinary teams of world-class scientists and build their track record as a computational drug hunter. This role is dedicated to driving preclinical small-molecule drug discovery projects from computational target assessment, virtual screening, lead identification, through lead optimization, together with our partners in adjacent departments.
Your impact:
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Contributing to the advancement of drug discovery projects by integrating data from all available sources to generate actionable insights in the form of molecular designs, new experiments, and testable IP-relevant hypotheses.
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Proactively seeking new opportunities for rational drug design across the portfolio and contributing to the assessment of new targets.
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Ensuring and facilitating transparent decision-making within the team, guided by clear decision criteria and based on thorough data analysis.
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Drive science and implementation of novel computational drug design techniques in trustworthy relationships and effective collaboration with internal and external partners.
Who you are
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You have a PhD and 3-5 years of professional experience and track record in the field, which enables you to directly impact drug discovery projects with CADD input.
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You are excited about driving drug discovery projects with CADD methods, knowledgeable in medicinal chemistry principles and the general drug development processes.
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You have a deep understanding of all aspects of CADD (chemoinformatics, data mining, structure-based design, computational chemistry, etc.) and enjoy applying your data analysis, programming, and problem-solving skills to drug design challenges. You are fluent in Python and have demonstrated experience with modern Python machine learning frameworks.
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You are fluent in English and have strong oral and written communication skills.
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You thrive in a dynamic, multi-disciplinary environment, which gives you full accountability for your own contributions and development.
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You are resourceful and flexible in problem-solving and enjoy working collaboratively and inclusively. You are dedicated to establishing a culture of mutual support, cross-training, continuous learning and self-organisation to meet project and functional goals. You are able to identify your top deliverables, finalise projects to achieve results, whilst assuming personal responsibility for outcomes.
Unwavering focus, collaborative teamwork and exceptional delivery are key behaviours that drive our mission of doing now what patients need next. Together, we can be transformative.
If you are passionate about contributing to a committed team and have the dedication to partnership and innovation, Roche is the place for you!
Every role at Roche plays a part in making a difference in patients’ lives.
Apply now and join us in making an impact!
Who we are
A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let’s build a healthier future, together.
Roche is an Equal Opportunity Employer.
Company
If you want to advance your career with a leader, consider Roche. We rank among the worlds foremost corporations providing innovative healthcare solutions, continuously investing in medical research and development. By preventing, diagnosing and treating a range of health disorders, our products and services have enhanced the health and quality of life of people around the world. Specifically, we focus on disease areas where the medical needs are greatest such as cancer, viral infections, disorders of the metabolic and central nervous systems, and inflammatory diseases. To address them, we have brought many highly effective drugs onto the market.
Be part of a winning company
Working at Roche means working at the forefront of innovation. Over the years, we have often engaged in new market trends or even set them and sometimes created entirely new markets. Our cutting-edge technologies and healthcare solutions were occasionally developed with unconventional methods but always with the highest standard of quality in mind.
Our Diagnostic division is the world leader in in-vitro diagnostics, our Pharmaceutical Division is the No. 1 supplier of cancer medicines.
Capitalizing on the exciting possibilities offered by genome research, our diagnostics and pharmaceuticals businesses also work together to develop integrated solutions that can be customized to individual patients' needs. As examples of our accomplishments, see our most recent awards.
Last but not least, we continue to grow. In an ever-changing industry, we are able to offer long-term organizational stability while permanently addressing new challenges. You will have the opportunity not only to learn and move forward but also to make your mark.
Thrive on our performance culture
You are used to giving your all to your career. Shouldn't your employer do the same?
As we keep reinventing ourselves, we depend on our people to take initiative and push ahead. That's why we value active, forward-looking self-starters willing to promote innovation in all aspects of our business. And since we look at competencies across functions and geographies, youll certainly be able to align your interests with our business needs.
As one way of showing our appreciation for your valuable work, we offer attractive compensation packages. Designed in line with our individual business locations, they make sure you will be able to meet the financial demands of your environment more than adequately. Also, we believe in having our employees share in the success of the company. Our employee share plan Roche Connect enables you to purchase shares at a 20% discount. It is currently available in 41 countries.
Enjoy our inspiring work environment
At Roche, some of our biggest breakthroughs have come from the sharing of wide-ranging perspectives. That’s why we value and celebrate different ideas. Our people come from across the globe, but what unites us is how much we care. Your experience is key to this vital exchange, which helps us develop the skills of more junior employees. And not only that: you will soon realize that it also inspires you to expand your own professional capabilities. One of the core elements of our culture is feedback. After all, sharing knowledge promotes the development of new ideas, which is one of our key competitive strengths. The Roche Europe Forum is one of several global platforms for exchanging information on business policy and strategy.
With our focus on natural, long-term growth, Roche depends on the contributions of talented and committed professionals like you who are determined to drive our progress. In turn, we make sure your work environment leaves you the space you need to attend to your personal goals, meet your family obligations, and pursue your professional development. We also have a variety of site-specific plans and programmes in place which offer flexible working-time models, sports and recreation offers, and more. This way we help you concentrate on your priorities resting assured that all aspects of your life are taken care of.
In short, think of Roche as a successful, forward-looking global player where your career will continue to flourish.
Company info
Location
Basel-Stadt
4070
Switzerland
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