Job Descriptionbr/br/pWe are currently looking for a 12-months (with the possibility to extend the contract to 24-months) Postdoctoral Fellowship contract in our Process Technology department in Münchwilen. The role sits at the interface of chemistry and digital innovation, focused on designing and evaluating human-in-the-loop methodologies that combine generative chemistry AI with expert synthetic knowledge to accelerate synthesis route scouting. You will collaborate across teams, benchmarking digital synthesis tools and identifying the most promising directions for adoption across Syngenta's synthesis programs. You will be given the opportunity to develop new skills while working at the cutting edge of chemistry, data science and AI. /ppYour responsibilities: /pullipDesign and execute structured evaluations of generative chemistry AI tools combined with expert chemical judgment /p /lilipDevelop and document reusable benchmarks based on internal route catalogs and external literature datasets /p /lilipInvestigate multiple methodological approaches for AI-assisted synthesis route improvement /p /lilipIntegrate digital synthesis tools into live route scouting activities /p /li /ulullipConduct literature reviews to identify and prioritize promising directions in generative chemistry /p /li /ulullipCapture and communicate findings through internal reports, presentations and potential scientific publications /p /li /ulbrQualificationsbr/br/ullipA PhD in digital chemistry, organic chemistry, cheminformatics, or a closely related field /p /li /ulullipSound knowledge of synthetic organic chemistry and retrosynthetic analysis /p /li /ulullipWorking knowledge of cheminformatics concepts: molecular representation (SMILES, InChI), reaction databases, retrosynthesis logic /p /li /ulullipFamiliarity with generative chemistry or AI-assisted synthesis planning tools (e.g., AiZynthFinder, ASKCOS, IBM RXN, or similar) is a plus /p /li /ulullipPython proficiency covering cheminformatics (RDKit), data analysis (pandas), version control (Git) and unit testing /p /li /ulullipAbility to critically evaluate and benchmark AI-generated synthesis routes against expert knowledge /p /li /ulullipComfortable working across chemical development and digital/data science teams /p /li /ulullipFluent English with strong written and verbal communication skills /p /li /ulbr/br/Additional Informationbr/br/pstrongWHAT WE OFFER /strong /pullipScientific and technical excellence at the intersection of chemistry and AI /p /li /ulullipContribution to valuable and impactful work, in a stimulating environment /p /li /ulullipWork in interdisciplinary teams spanning Process Technology, Medicinal Chemistry, CAST and Digital/AI. An open and collaborative work atmosphere /p /li /ulullipContinuous professional development and high scientific standards as foundations of our culture /p /li /ulullipAccess to internal route catalogs, digital synthesis platforms and experienced colleagues across chemistry and data science /p /li /ulullipA responsible position with adequate training and meaningful scientific challenges /p /li /ulpInterested? We are looking for your application! Along with your Cover Letter and CV please provide a Research Summary of 2–5 pages. /ppSyngenta is an Equal Opportunity Employer and does not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. /p