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Head of upstream processing (usp)

Geroldswil
evitria AG
EUR 125’000 - EUR 150’000 pro Jahr
Inserat online seit: Veröffentlicht vor 11 Std.
Beschreibung

We are seeking an experienced and hands‑on Head of Upstream Processing (USP) to lead upstream development activities for recombinant protein production in a dynamic biotech environment.

RESPONSIBILITIES

Lead and develop the USP team (scientists and technicians)

Maintain a high level of training and scientific expertise within the team

Mentor and support staff and actively support employee development

Allocate and prioritize work within the team in alignment with the Head of Operations

Provide scientific leadership in molecular biology, cell culture, and antibody expression

Drive upstream process development for recombinant antibodies and complex antibody formats with excellent knowledge of cloning strategy, sequence design and DNA synthesis

Establish scalable and robust USP workflows suitable for tech transfer and manufacturing

Support business activities by proposing and reviewing USP‑specific components in customer quotations when required

Continuously assess state‑of‑the‑art technologies and scientific developments

Promote scientific excellence by identifying and initiating suitable development projects

Ensure scientific standards, documentation quality, and compliance with internal procedures

Define USP process steps, associated SOPs, and work instructions together with the team

Lead the prevention and resolution of quality defects in production within the area of USP

Ensure proper functionality, maintenance, and qualification status of equipment within USP

Manage cross‑functional projects and coordinate activities across departments

Collaborate closely with DSP and project management teams

QUALIFICATIONS

MSc or PhD in Biotechnology, Molecular Biology, or a related field

Several years of industry experience in upstream processing of biologics, ideally antibodies

Strong expertise in antibody formats and recombinant protein expression

Deep knowledge of molecular biology techniques and mammalian cell culture systems

Proven leadership experience managing scientific teams

Hands‑on, pragmatic, and solution‑oriented mindset

Strong communication and cross‑functional collaboration skills

Experience in small biotech or startup environments is highly desirable

Fluency in English and/or German

ABOUT EVITRIA
evitria is specialized in CHO‑based transient expression of antibodies (including bispecifics and fusion proteins). With a track record of more than 140,000 successful antibody production runs for our clients, we offer fast and reliable project execution at high quality standards.

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