"Expect to grow", personally and professionally: At Siegfried, we offer exciting challenges opportunities to showcase your talents. As a trusted and respected partner to the pharmaceutical industry, we uphold the highest standards in safety, quality and sustainability, while fostering a culture that empowers you to thrive. Join a rapidly expanding global company, where diverse perspectives and experiences come together in a collaborative environment. Here, you'll find a workplace that values both collective success and your individual contributions—offering long-term opportunities to grow and make an impact.
Your Role:
Siegfried DINAMIQS is a Contract Development and Manufacturing Organization (CDMO) based in Schlieren-Zurich, Switzerland, specializing in the manufacturing of viral vector gene therapies. At DINAMIQS we offer a comprehensive range of services, including vector design optimization, cutting-edge process development and analytics, as well as manufacturing. With a R&D facility running since 2022 and a newly constructed GMP facility, we are dedicated to supporting gene therapy projects with scalable and efficient solutions. DINAMIQS became part of Siegfried's global network in 2023 and is now looking to grow its dedicated team of experts by hiring a Head of Manufacturing and MSAT. If you are highly motivated, self-driven, and passionate about driving operational excellence in a dynamic environment, you are the person we are looking for:
* Organisethemanufacturing and MSAT sector to ensure an on-time on budgetproduction
* Leadtheupstream, downstream, fill-finish and support manufacturing operations to ensuresafeandcompliantdelivery of clinical and commercial products
* Lead and further develop the MSAT function, ensuring robust technology transfer, process validation, lifecycle management, and technical troubleshooting
* Drive process optimization, scale-up/scale-down activities, process characterization, and continued process verification
* Ensure full compliance with GMP regulations, internal quality systems, and global regulatory requirements (FDA, EMA, ICH, PIC/S)
* Support and lead investigations, deviations, CAPAs, risk assessments, and root cause analyses in close collaboration with QA, QC, and Regulatory Affairs
Your Profile:
* Advanced degree in Biotechnology, Bioprocess Engineering, Chemical Engineering or a related life sciences field
* Proven leadership experience in MSATand manufacturingwithin a GMP-regulated biopharmaceutical environment, ideally in biologics or ATMPs space
* Strong expertise in upstream and downstream bioprocessing and related analytical methods, ideally using viral vectors
* Experience on sterile drug product manufacturing, including F&F operations
* Solid understanding of regulatory guidelines and experience supporting audits and inspections
* Experience with digital manufacturing systems (LIMS, eBR, SAP, automation platforms,...) would be desired
* Strong communication, problem-solving, and organizational skills with a hands‑on, solution‑oriented mindset
* High skills in written and spoken English; German would be a plus
Your Benefits:
* A unique and amazing work experience, being part of one of the most dynamic,diverseand inclusive CDMOs in the industry
* Competitive and attractive compensation
* 5 weeks holidays and flexible working hours make it possible to combine family, leisuretimeand career
* Impactful Work: Make a significant difference through innovativegene therapyprojects
* Learning Opportunities: Develop diverse skills in a dynamic environment
* Fast-Paced Environment: See results quickly andenjoy creative freedom in defining your operating model and go to market strategy
Are you interested in joining a motivated team with aninclusive and collaborativeculture? Then take the next step and send us your application.
Founded in 1873 in Zofingen, Switzerland, Siegfried has grown into a global network of 13 sites across three continents. With a team of more than 3,800 highly skilled professionals, we take the innovations of our pharmaceutical customers to industrial scale and manufacture safe drugs for patients worldwide. As a fully integrated CDMO, Siegfried is one of the few organizations today that can carry out the development and manufacturing of APIs and finished dosage forms under one roof. This unique combination of know-how and experience makes us the most trusted partner in the pharmaceutical industry.
#J-18808-Ljbffr