Research Scientist / Senior Scientist – Protein Sciences (Novartis Biomedical Research)
Join to apply for the Research Scientist / Senior Scientist – Protein Sciences (Novartis Biomedical Research) role at Novartis
Research Scientist / Senior Scientist – Protein Sciences (Novartis Biomedical Research)
Join to apply for the Research Scientist / Senior Scientist – Protein Sciences (Novartis Biomedical Research) role at Novartis
Summary
Novartis Biomedical Research (BR) serves as the innovation engine of Novartis, driving cutting-edge approaches to deliver therapeutic breakthroughs for patients. Within BR, the Discovery Sciences department pioneers early-stage drug discovery and promotes innovative therapeutics to tackle challenging disease targets.
Summary
Novartis Biomedical Research (BR) serves as the innovation engine of Novartis, driving cutting-edge approaches to deliver therapeutic breakthroughs for patients. Within BR, the Discovery Sciences department pioneers early-stage drug discovery and promotes innovative therapeutics to tackle challenging disease targets.
The Protein Sciences group in Discovery Sciences is an interdisciplinary team specializing in protein biochemistry, biophysics, NMR, X-ray crystallography, and electron microscopy. Our focus is to enable target-based hit identification, validation, and structure-guided drug discovery, with an emphasis on challenging targets such as membrane proteins.
We are seeking a highly skilled and motivated Research Scientist / Senior Scientist with a strong background in protein expression and purification, ideally including experience with membrane proteins, to join our team in Basel, Switzerland. This is a unique opportunity to contribute to drug discovery across multiple disease areas within a dynamic, collaborative environment that values curiosity, innovation, and teamwork.
Responsibilities
About the Role
You Will Work To Produce High-quality Proteins For Drug Discovery, Focusing On Small Molecule Hit Generation, Validation, And Structural Biology. Key Responsibilities Include:
* Express proteins insect and mammalian cell culture systems.
* Purify proteins using chromatography techniques and FPLC equipment to enable downstream assays and structural biology for drug discovery.
* Collaborate with team members to enable cryo-EM structural characterization of membrane proteins.
* Optimize protocols and processes through literature research, ideation and hands-on wet lab exploration.
* Work closely in a matrix setting with lab associates and present findings to project teams.
Minimum Requirements
* Completed apprenticeship as a laboratory technician with 2 years of practical work experience or Bachelor/Masters in biochemistry, biology, molecular biology, life sciences, or a related field with strong experience in wet lab work.
* In-depth theoretical knowledge and hands-on experience in protein biochemistry, including expression, purification, and characterization.
* Strong collaboration, organizational, and communication skills in oral and written English, with the ability to effectively present results in team settings.
* Proactive interest in acquiring new techniques in protein biochemistry, biophysics, and structural biology.
Desirable Requirements
* Hands-on experience in membrane protein expression, purification, characterization, and familiarity with cryo-EM workflows (sample preparation, grid handling).
* Prior exposure to an industrial research environment.
* Familiarity with software tools for structural analysis and AI driven protein construct design (PyMol, AlphaFold, etc.).
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture
Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network
Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards
Seniority level
* Seniority level
Mid-Senior level
Employment type
* Employment type
Full-time
Job function
* Job function
Other
* Industries
Pharmaceutical Manufacturing
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