PhD Student in Engineering Organs-on-Chip for Lymphatic–Vascular Studies (100%)
Be among the first 25 applicants.
PhD-Position in Engineering Organs-on-Chip at Universität Bern. Eine spannende Gelegenheit für innovative Forschung.
Responsibilities
* Entwicklung von Organ-on-Chip-Systemen zur Untersuchung von Lymphgefäßen.
* Gestaltung und Optimierung mikrofluidischer Chips für biologische Anwendungen.
* Zusammenarbeit mit führenden Experten und Präsentation von Ergebnissen.
* Model development: Collaborate with research partners in Bern and Zurich to develop multi-compartment OOC systems integrating blood and lymphatic vasculature with key mechanical cues of the lung microenvironment.
* Characterization: Design chips, fabricate & optimize using state-of-the-art microfabrication techniques and characterize chip performance (fluidics, mechanics, and reproducibility).
* Method development: Design and implement specific functional read-outs and quantitative assays to assess vascular‑lymphatic interactions.
* Collaboration & dissemination: work closely with research partners, contribute to publications and present results at international conferences.
Skills
* M.Sc. in Maschinenbau, Biomedizintechnik oder verwandtem Bereich erforderlich.
* Starke Kenntnisse in Mikrofluidik und Zellkulturtechniken.
* Erfahrung in CAD-Design und Programmierkenntnisse in Python.
* Strong theoretical and practical understanding of fluid dynamics, fluidic circuit design, and numerical simulation (e.g., COMSOL Multiphysics or ANSYS).
* Experience in designing, optimizing and validating microfluidic systems for biological applications.
* Hands‑on experience in developing and prototyping novel microfluidic systems (soft lithography, 3D printing).
* Practical experience with cell culture in microfluidic systems, co‑culture approaches, and skilled in fluorescence microscopy and image analysis.
* Proficiency in Python, MATLAB, or R for data analysis and automation of experimental workflows.
Requirements
* MSc in Mechanical Engineering, Biomedical Engineering, Microsystems Engineering or a related field.
* Excellent oral and written communication skills in English.
* Creative, organized, self‑motivated – able to work independently and within a multidisciplinary team.
What We Offer
* A stimulating interdisciplinary research environment linking bioengineering, cell biology and translational medicine.
* Access to state‑of‑the‑art microfluidic, organs‑on‑chip and imaging facilities.
* Opportunities to collaborate with leading experts in vascular and lymphatic biology and COPD.
* The successful PhD candidate will be enrolled in the Graduate School of Cellular and Biomedical Sciences (GCB).
* Salary according to the SNSF regulations.
* A vibrant research setting in Bern, Switzerland’s capital, surrounded by the Aare river and the Bernese Alps.
* The review of applications will start on December 1st, 2025. The position will remain open until it is filled.
In your application, please refer to myScience.ch and reference JobID68726.
Website: www.artorg.unibe.ch/research/ooc/index_eng.html
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