Upstream or Downstream Process Scientist – Clinical Manufacturing
Vevey, Switzerland – Full-time, 4-month contract (possibility of extension)
Company Description
This leading biopharmaceutical company, based in Vevey, Switzerland, is at the forefront of innovation in large-scale biologics manufacturing. With a strong focus on supporting early-phase clinical programs, the site specializes in producing materials for Phase I and II clinical trials using state-of-the-art technologies and scalable bioprocessing systems.
Job Description
As an Upstream Process (USP) Scientist or Downstream Process (DSP) Scientist, you will play a vital role in supporting clinical manufacturing operations for biologics ranging from 200L to 2000L scale. In these roles, you will support the execution of pre-clinical and clinical campaigns, ensuring compliance with GMP and safety standards while contributing to the integration of new technologies and continuous improvement of bioprocesses.
Working in close collaboration with cross-functional teams - such as Production, QA, QC, and Engineering - you will be responsible for technical execution, batch documentation, deviation management, and supporting process implementation for either cell culture (USP) or purification (DSP).
Key Responsibilities:
* Perform Electronic Batch Record (EBR) reviews using MES (Manufacturing Execution System)
* Lead and close deviations, investigations, CAPAs, and critical control point (CCP) actions in alignment with the site’s quality plan
* Ensure compliance with GMP, safety protocols, and internal quality standards
* Maintain an up-to-date training plan and adhere to individual training requirements
* Proactively report unexpected events and ensure full traceability of assigned tasks
* Follow site EHS procedures and immediately report hazardous conditions or behaviors
* Wear and maintain proper use of PPE and safety devices
* Suggest improvements and actively contribute to a culture of safety and quality
Essential Requirements:
* PhD in Chemistry, Biology, Biotechnology, or a related field with 1–2 years of industry experience OR MSc/Engineering degree with 4–5 years of relevant experience OR Technical degree with 10+ years of relevant experience in GMP manufacturing
* Strong expertise in either:
* USP: Fed-batch and/or perfusion cell culture
* DSP: Chromatography, filtration, and purification operations
1. Working knowledge of GMP and BPF regulations
2. Proficiency in MES and the ability to conduct electronic batch record reviews
3. Strong communication and teamwork skills, with the ability to collaborate across departments (Production, QA, QC, Tech Ops)
4. English fluency required; French is a strong plus
Desirable Experience:
* Familiarity with TrackWise, SAP, LIMS, and standard office IT tools
* Prior experience in clinical or commercial pharmaceutical production in either upstream or downstream roles
* Demonstrated experience in deviation/CAPA management
Additional Insights:
* Location: Vevey, Switzerland (on-site role)
* Contract Type: 4-month contract with strong potential for extension
* Start Date: ASAP (flexible depending on availability)
* Language Requirements: English required; French preferred
Interested?
Send your CV to Khanyi Mabena at k.mabena@panda-int.com or reach out directly at+41445514407 to learn more.
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