Roche Postdoctoral Fellowship (RPF) on Alveolar Regeneration in Homeostasis and Inflammatory Disease
Join Roche as a highly motivated postdoctoral fellow in the Immunology Discovery group of the Cardiovascular Metabolism and Immunology Department. The successful candidate will investigate molecular pathways involved in alveolar cell regeneration and function under homeostatic and inflammatory conditions, focusing on Wnt and other signaling pathways using pharmacologic modulators.
Key Responsibilities:
1. Culture of human alveolar and airway organoids
2. Investigate disease-relevant perturbations to identify molecular states
3. Perform phenotypic and molecular characterization (immunofluorescence, flow cytometry, scRNA-seq)
4. Use pharmacological modulators to understand pathways in alveolar regeneration
5. Assess how pathway modulation affects alveolar progenitor cell function in disease conditions
Qualifications:
* PhD in Molecular Biology, Cell Biology, Developmental Biology, Pharmacology, or related field
* Within four years of completing your PhD at the start of the project
* Strong background in cell signaling, organoid culture, and Wnt pathways
* Experience with high-throughput screening, genetic engineering, iPSC technology, and computational analysis is desirable
* Excellent problem-solving skills and ability to work independently and in teams
This position is funded by the Roche Postdoctoral Fellowship Programme, aimed at fostering scientific leadership. The fellowship duration is initially two years, with a possible extension to three, based in Basel, Switzerland. The start date is flexible; please specify your preference in your application.
Application requirements include your CV, motivation letter, and publication list. Roche values diversity and equal opportunity, welcoming applicants from various backgrounds.
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