About the Program
The RiSE program (Roche Internships for Scientific Exchange) is a highly competitive student research program at Roche. It offers the most talented graduate and medical degree students the opportunity to be fully integrated into our interdisciplinary and international industry R&D environment.
Position
As a RiSE student in the NRD DTA you will join our group in Neuroimmunology at the Roche Innovation Center Basel, Switzerland. This project investigates the link between microglial lipid accumulation and their cellular dysfunction in neurodegenerative disease.
Opportunity
* Characterizing microglia in human tissue and utilizing pharmacological interventions that target lipid metabolism
* Culturing, differentiation and characterization of human iPSC-derived microglia
* Performing in vitro and ex vivo functional assays to elucidate the impact of pharmacological agents on microglial activation, lipid profiles and phagocytosis
* Utilize advanced immunohistochemical techniques to characterize microglial phenotypes in human tissue
* Work closely within a diverse team composed of scientists, research associates and interns
* Present your progress at internal meetings and contribute to publications
* Be hosted and mentored by a Roche scientist who will guide you through your research and provide you with the needed work infrastructure and collaborative network
Who You Are
* Graduated less than a year ago or enrolled in a PhD or medical degree program at a university
* Looking to expand your experience with an industry internship
* Proficient in maintaining and running diverse assays with iPSC-derived microglia
* Background in cellular neurobiology, neuroimmunology, lipid metabolism or other related subject
* Proven track record in cell culture, cellular assays and biochemistry (dose response treatments, live cell imaging, confocal microscopy, IHC/ICC, ELISA, qPCR / WB)
* Independent, proactive, and willing to work in a highly collaborative and dynamic research environment
Additional Information
The preferred start date of the internship is July 2026 or upon availability. Please clearly indicate your preferred starting date on your cover letter.
Roche is an Equal Opportunity Employer.
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