The Position
Digital health technology is revolutionizing the way we develop personalized medicines for patients. Roche is committed to creating community- and regulator-accepted digital endpoints and outcomes that redefine how we measure disease progression in clinical drug trials, making them accessible to Biopharma companies and the research community.
Job Mission
We are an integrated team of scientists, technologists, data analysts, and operationalization experts in Roche Information Solutions, leveraging mobile technologies like smartphones and wearables to collect objective and continuous sensor data from patients in clinical trials.
We co-create innovative digital remote monitoring concepts for sensitive and meaningful drug development endpoints, implement them in technology solutions, develop health-related outcome measures with the data, seek community- and regulatory acceptance of corresponding endpoints, and offer them to biopharma companies and research institutes for use in clinical trials.
Your Impact
You will be responsible for:
* Being the scientific product owner of our library of signal processing algorithms to extract meaningful features from raw sensor data collected with our digital health technology tools.
* Overseeing and developing novel and improving existing algorithms.
* Developing and executing strategies for validation of algorithms and devices.
* Co-developing the roadmap for library maintenance and extension together with the technical product owner of the library.
* Supporting and building the lifecycle of algorithm development from early research up to a computer system validated algorithm to be used in our products.
* Working together with the dBM scientific solutions lead and the dBM data solutions lead to support the development of novel data insights products around our digital health technology tools.
* Supporting the UI/UX design of novel digital health technologies to ensure meaningful data collection from an algorithmic perspective.
* Scientifically supporting customer interactions by providing data analysis support for customer questions and supporting the development of material for sales collateral.
* Leading activities in matrix teams.
* Being the main interface to other internal and external digital biomarker algorithm development teams.
* Driving the understanding of data analysis results by clinical development programs through the development of compelling narratives and presentations.
* Writing manuscripts for peer-reviewed journal articles to establish the biological, clinical, and patient relevance of data collected in novel digital biomarker approaches.
Requirements
* A very good university degree in engineering, mathematics, statistics, natural sciences, or informatics.
* 5+ years of hands-on experience with signal processing accelerometer, gyroscope, audio) of data collected with digital health technologies, optimally collected in neurological diseases in a clinical trial context.
* Understanding of the V3 framework and similar approaches.
* A track record of algorithm validation.
* ML/AI experience.
* Experience in working in a goal-oriented manner with the customer in mind.
* Strong experience with analyzing and visualizing large data sets.
* Experience of working collaboratively within a large team and managing your time against competing demands.
* A track record of writing compelling publications in high-impact, peer-reviewed journals.
* Proficient in Python (optional: R or similar software packages/languages).
* Excellent English language skills and excellent writing abilities.